Medspray Technology • Medspray

Micro- and nanotechnology

Medspray uses established micro- and nanotechnology processes to manufacture spray nozzles. The orifices of our spray nozzles are extremely tiny (1 to 30 micrometer, for reference: a human hair is 70 micrometers thick). At the extensive Nanolab facilities of Twente University our operators create silicon nozzle chips for R&D purposes.

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Rayleigh sprays

Medspray owns six patent families concerning the spray nozzle unit technology. Our spray nozzle units are based on plain orifice nozzles, creating Rayleigh jets. A 2 micron hole creates a jet, breaking up into mono-disperse (meaning all droplets have the same size) 4 micron droplet trains. The diameter of the droplets is twice the size of the orifice. The hole size can be engineered to meet specific requirements of devices. Spray nozzle chips are made with technologies generally seen in computer chips, but our chips do not have electronic functions, they are purely a mechanical structure.

Pressing water through the Medspray nozzle results in a jet which automatically breaks up in droplets (Rayleigh breakup). The spray is mono-disperse. All droplets are twice the size of the hole. By changing the diameter of the hole in the spray nozzle, the droplet size can be engineered for optimal performance.

Spray Nozzle Units

Spray nozzles are created batch-wise. We produce several thousand nozzles from a single silicon wafer. To meet growing demands, Medspray’s current focus is on scaling up production of spray nozzle units to several million pieces annually. This way, we can upscale our back end processes like packaging the nozzle chip in the plastic spray nozzle unit. The assembly is now done in our clean room facility in semi-automated and fully automated production lines.

Clean room manufacturing and assembly

The spray nozzles are assembled in ISO 8 cleanrooms, because they are part of the primary package of the drug formulation for some pharmaceutical applications.

High tech,
and future proof!

Our assembly clean rooms are located within the High Tech Factory. Our spray nozzle unit assembly is done in our ISO Class 8 cleanrooms. Small series for clinical trials can be produced on semiautomated lines, giving maximum flexibility. However, we still use automated welding steps to maintain a constant product quality. Larger series are made on our fully automated line.

Technology